Genetic Risk and Lifestyle Risks Independent in Breast Cancer

June 18, 2010 09:43pm EST 
Genetic Risk and Lifestyle Risks Independent in Breast Cancer
A large study of the British Million Women Study has shown that the lifestyle, or environmental, risk factors for breast cancer are not linked to the genetic risk factors that sometimes cause the disease.

The study, including over 17,000 women participants, found that gene variants that raise the risk of breast cancer only add to a woman’s likelihood to develop the disease. In the past, it was thought that genetic risks multiply a woman’s risk to develop breast cancer, making regular exercise and healthy living extremely important.

The team, working out of Oxford University’s cancer epidemiology unit, studied 5 genetic factors leading to higher risk of breast cancer and 13 genetic risk variants. After a comparison with 10 environmental risk factors, the researchers found that there was no significant evidence of interaction between the genetic and lifestyle risk factors.

With the new findings, women who are at genetic risk for breast cancer know that they can significantly limit their risk for breast cancer with healthy living. Genetic variants are proven to make only a small impact on breast cancer risk, making lifestyle factors much more valuable when preventing breast cancer.
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